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Streszczenie:
This article provides a comprehensive review of the chemistry, production technology, and utilization of nanolime. Particular attention is given to the synthesis of Ca(OH)2 nanoparticles through both bottom-up and top-down approaches, highlighting how modern techniques enable precise control of particle size, morphology, and stability. The physicochemical properties of nanolime are discussed in relation to its role as a highly reactive, multifunctional additive, i.a., for cementitious systems, asphalt, and autoclaved products. Its applications are explored with emphasis on performance improvement in construction engineering, including enhanced strength, durability, self-healing potential, and compatibility with low-carbon binders. Beyond construction, nanolime is also examined as a material with relevance to environmental protection, CO2 sequestration, and heritage conservation. The review demonstrates that nanolime is a versatile and strategic material whose properties can be tailored to specific engineering needs, though challenges such as agglomeration, carbonation control, scalability, and long-term durability remain. Future research directions are outlined, focusing on sustainable production methods, functional integration into next-generation binders, and cross-disciplinary applications

Słowa kluczowe:
nanolime, nanolime synthesis, cement-based materials, CO2 capture, self-healing, heritage conservation

Streszczenie:
The prevalence of renal diseases is rising and reaching 5–15% of the adult population. Renal damage is associated with disturbances of body homeostasis and the loss of equilibrium between exogenous and endogenous elements including drugs and metabolites. Studies indicate that renal diseases are influenced not only by environmental but also by genetic factors. In some cases the disease is caused by mutation in a single gene and at that time severity depends on the presence of one or two utated alleles. In other cases, renal disease is associated with the presence of alteration within a gene or genes, but environmental factors are also necessary for the development of disease. Therefore, it seems that the analysis of genetic aspects should be a natural component of clinical and xperimental studies. The goal of personalized medicine is to determine the right drug,for the right patient,at the right time. Whole-genome examinations may help to change the approach to the disease and the patient resulting in the creation of“personalized medicine”with new diagnostic and treatment strategies designed on the basis of genetic background of each individual. The identification of high-risk patients in pharmacogenomics analyses will help to avoid many unwarranted side effects while optimizing treatment efficacy for individual patients. Personalized therapies for kidney diseases are still at the preliminary stage mainly due to high costs of such analyses and the complex nature of human genome. This review will focus on several areas of interest: renal disease pathogenesis, diagnosis, treatment, rate of progression and the prediction ofprognosis.

Słowa kluczowe:
renal diseases, personalized medicine, treatment, diagnosis, biomarkers