1. |
Olusegun S.♦, Souza Guilhermina de O.♦, Sutuła S.♦, Osial M., Krajewski M.♦, Pękała M.♦, Sobczak K.♦, Felis E.♦, Krysiński P.♦, Methotrexate anti-cancer drug removal using Gd-doped Fe3O4: Adsorption mechanism, thermal desorption and reusability,
Groundwater for Sustainable Development, ISSN: 2352-801X, DOI: 10.1016/j.gsd.2024.101103, Vol.25, pp.1-9, 2024Słowa kluczowe: Adsorption,Thermal desorption,Gd-doped Fe3O4,Methotrexate Afiliacje autorów:
Olusegun S. | - | inna afiliacja | Souza Guilhermina de O. | - | inna afiliacja | Sutuła S. | - | inna afiliacja | Osial M. | - | IPPT PAN | Krajewski M. | - | inna afiliacja | Pękała M. | - | inna afiliacja | Sobczak K. | - | inna afiliacja | Felis E. | - | inna afiliacja | Krysiński P. | - | inna afiliacja |
| | 40p. |
2. |
Olusegun S.♦, Osial M., Majkowska-Pilip A.♦, Żelechowska-Matysiak K.♦, Nieciecka D.♦, Krajewski M.♦, Pękała M.♦, Krysiński P.♦, Synthesis and characterization of Sr2+ and Gd3+ doped magnetite nanoparticles for magnetic hyperthermia and drug delivery application,
CERAMICS INTERNATIONAL, ISSN: 0272-8842, DOI: 10.1016/j.ceramint.2023.03.102, pp.1-10, 2023Streszczenie: Commendable efforts have been gingered towards the fight against cancer. Nevertheless, it remains a major public health concern due to its predominant cause of death globally. Given this, we synthesized two different nanoparticles, Sr2+ and Gd3+ doped magnetite for magnetic hyperthermia and drug delivery application. Based on the characterization, the diffractogram shows that only one phase related to magnetite with a crystallite size of 10 nm was formed. TEM images revealed nanoparticles of spherical shapes of approximately 12 nm. There is no difference in magnetic saturation of the as-received synthesized samples (Fe3O4@Sr and Fe3O4@Gd), while the BET-specific surface area of Fe3O4@Gd is 8 m2 g−1 higher than Fe3O4@Sr. The heat generation in alternating magnetic field (the magnetic hyperthermia) of Fe3O4@Sr functionalized with citric acid and loaded with 5- fluorouracil (Fe3O4@Sr@CA@5-flu) is slower than Fe3O4@Gd@CA@5-flu. The specific absorption rate (SAR) of Fe3O4@Gd@CA@5-flu, 112.0 ± 10.4 W g−1 was found to be higher than that of Fe3O4@Sr@CA@5-flu. The thermogram shows that 11% of the drug was successfully loaded on Fe3O4@Gd@CA@5-flu. The release of the antitumor drug by the synthesized nanoparticle drug carriers for ovarian cancer (SKOV-3 cells) therapy showed that more than 50% of the cancer cell’s viability was reduced after 72 h of incubation. The synthesized nanoparticles demonstrated a promising drug carrier for the treatment of SKOV-3 cells. Afiliacje autorów:
Olusegun S. | - | inna afiliacja | Osial M. | - | IPPT PAN | Majkowska-Pilip A. | - | inna afiliacja | Żelechowska-Matysiak K. | - | inna afiliacja | Nieciecka D. | - | inna afiliacja | Krajewski M. | - | inna afiliacja | Pękała M. | - | inna afiliacja | Krysiński P. | - | inna afiliacja |
| | 100p. |
3. |
Olusegun S.♦, Osial M., Souza Taiane G.♦, Krajewski M.♦, Rodrigues G.L.S.♦, Pękała M.♦, Krysiński P.♦, Comparative characteristics and enhanced removal of tetracycline and ceftriaxone by Fe3 O 4 -lignin and Fe 3 O4 -carbon-based lignin: Mechanism, thermodynamic evaluation, and DFT calculation,
Journal of Molecular Liquids, ISSN: 0167-7322, DOI: 10.1016/j.molliq.2022.121075, Vol.371, No.121075, pp.1-16, 2023Streszczenie: In this study, eco-friendly Fe3O4-lignin (FeL) and Fe3O4-carbon-based lignin (FeCL) were synthesized, characterized, and applied for the adsorption of tetracycline (TRC) and ceftriaxone (CEF). Comparative characterization showed that the BET-specific surface area of FeCL is 27 m2/g more than that of FeL. The difference in their morphologies is insignificant, and the particle sizes range between 5 and 15 nm. There is a reduction in the oxygen content and hydroxyl group of FeCL as shown from the EDS and FTIR spectra respectively, compared with FeL. The adsorption capacity for the removal of TRC at 333 K is 156 and 148 mg g−1 by FeL and FeCL, respectively; while that of CEF are virtually the same. FeL and FeCL adsorption capacity for TRC increases with temperatures (endothermic), but decreases (exothermic) for CEF. The combination of experimental and computational approaches gave insight into the mechanisms of the adsorption process. The mechanisms of TRC and CEF adsorption by FeL and FeCL are the electrostatic attraction, hydrophobic, and π-π interaction, while only FeL shows the possibility of hydrogen bond with both TRC and CEF. The study demonstrated that the synthesized material can be reused for up to 3 cycles without an alarming loss of efficiency capacity.
Graphical abstract Słowa kluczowe: Lignin,antibiotics,Adsorption mechanisms,Thermodynamics Afiliacje autorów:
Olusegun S. | - | inna afiliacja | Osial M. | - | IPPT PAN | Souza Taiane G. | - | inna afiliacja | Krajewski M. | - | inna afiliacja | Rodrigues G.L.S. | - | inna afiliacja | Pękała M. | - | inna afiliacja | Krysiński P. | - | inna afiliacja |
| | 100p. |
4. |
Gawęda W.♦, Osial M.♦, Żuk M.T.♦, Pękała M.♦, Bilewicz A.♦, Krysiński P.♦, Lanthanide-doped SPIONs bioconjugation with trastuzumab for potential multimodal anticancer activity and magnetic hyperthermia,
Nanomaterials, ISSN: 2079-4991, DOI: 10.3390/nano10020288, Vol.10, No.2, pp.1-14, 2020Słowa kluczowe: superparamagnetc iron oxide nanoparticles, SPIONs, trastuzumab, magnetic hyperthermia, antitumor therapy Afiliacje autorów:
Gawęda W. | - | inna afiliacja | Osial M. | - | inna afiliacja | Żuk M.T. | - | NanoThea Inc. (PL) | Pękała M. | - | inna afiliacja | Bilewicz A. | - | inna afiliacja | Krysiński P. | - | inna afiliacja |
| | 70p. |
5. |
Osial M.♦, Rybicka P.♦, Pękała M.♦, Cichowicz G.♦, Cyrański Michał K.♦, Krysiński P.♦, Easy synthesis and characterization of holmium-doped SPIONs,
Nanomaterials, ISSN: 2079-4991, DOI: 10.3390/nano8060430, Vol.8, No.6, pp.1-15, 2018Słowa kluczowe: superparamagnetic iron oxide nanoparticles, SPIONs, rare-earth doping, holmium, endoradiotherapy Afiliacje autorów:
Osial M. | - | inna afiliacja | Rybicka P. | - | inna afiliacja | Pękała M. | - | inna afiliacja | Cichowicz G. | - | inna afiliacja | Cyrański Michał K. | - | inna afiliacja | Krysiński P. | - | inna afiliacja |
| | 35p. |